Lipoblastoma
Synonyms: Fetal lipoma, embryonal lipoma
Embryonal fatty tumour of infants
Quick Facts
Behaviour
Benign
Category
Soft tissue
Synonyms
- Fetal lipoma
- embryonal lipoma
Category
Soft tissue
Behaviour
Benign
Gender
Male
Tissue of Origin
Adipose
Epidemiology
- Benign embryonal white fat
- Presents in infants and young children
- 75-90% in patients younger than 3
Clinical Features
- Soft tissue mass
- Usually painless and Slow-growing
- May involve fascial compartments
Location
- Lower extremity most common
- Upper extremity
- Trunk
Imaging
- MRI: well-defined fat and myxoid components
- T2 bright areas mixed with lipid
Pathology
- Primitive mesenchymal cells and immature fat
- Myxoid stroma
- No atypia
Genetics
PLAG1 rearrangements common
Treatment
- Marginal excision curative
- Observation if asymptomatic
Prognosis
Excellent - no malignant potential
Key Points
- Embryonal fatty tumour of infants
- Benign despite somewhat immature appearance
Workup - Blood Tests
No blood tests required
Workup - Local Imaging
MRI - characterises extent and fat composition
Workup - Biopsy
Biopsy if diagnosis uncertain
Workup - Staging
No staging required
Workup - Other
Complete excision standard when feasible
Medical disclaimer
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