BenignBone
Epithelioid Haemangioma of Bone
Benign bone counterpart of soft tissue epithelioid haemangioma
Quick Facts
Behaviour
Benign
Category
Bone
Category
Bone
Behaviour
Benign
Gender
M = F
Tissue of Origin
Vascular
Epidemiology
- Rare benign vascular tumour of bone
- Adults most commonly affected
- Skull and jaw predilection
Clinical Features
- Pain and swelling
- Lytic bone lesion on imaging
- May involve soft tissue
Location
- Skull
- Jaw
- Long bones
Imaging
- Lytic lesion with cortical expansion
- Soft tissue extension may be present
Pathology
- Epithelioid endothelial cells lining vascular channels
- ZFP36-FOSB fusion
- CD31, ERG, FOSB positive
Genetics
ZFP36-FOSB or similar FOSB fusions
Treatment
Curettage or excision curative
Prognosis
Excellent - benign with very low recurrence
Key Points
- Benign bone counterpart of soft tissue epithelioid haemangioma
- FOSB fusions are characteristic
- Curettage usually curative
Workup - Blood Tests
None specific
Workup - Local Imaging
- Plain radiograph
- MRI for extent
Workup - Biopsy
Biopsy with FOSB IHC
Workup - Staging
Not required
Medical disclaimer
The content on Sarcopedia is for educational and informational purposes only and does not constitute medical advice. It is not intended to be a substitute for professional medical diagnosis or treatment. Always consult with a qualified physician regarding any health concerns or before starting any new treatment. Reliance on any information provided on this site is solely at your own risk.