BenignSoft tissue
Cellular Angiofibroma
Benign genital/inguinoscrotal soft tissue tumour
Quick Facts
Behaviour
Benign
Category
Soft tissue
Category
Soft tissue
Behaviour
Benign
Gender
M = F
Tissue of Origin
Fibrous
Epidemiology
- Rare benign spindle cell tumour
- Adults most commonly affected
Clinical Features
- Painless well-circumscribed mass in vulva, inguinal, or scrotal region
- Slowly growing
Location
- Vulva
- Scrotum and inguinal region
- Perineum
Imaging
MRI: well-defined, enhancing soft tissue mass
Pathology
- Cellular spindle cell proliferation with thick-walled vessels
- No significant atypia
- RB1 loss
Genetics
RB1 deletion
Treatment
Simple excision curative
Prognosis
- Excellent - recurrence after complete excision is rare
- No malignant potential
Key Points
- Benign genital/inguinoscrotal soft tissue tumour
- RB1 loss is characteristic
- Simple excision curative
Workup - Blood Tests
None required
Workup - Local Imaging
MRI for local characterisation
Workup - Biopsy
Excisional biopsy
Workup - Staging
No staging required
Follow-up Summary
Medical disclaimer
The content on Sarcopedia is for educational and informational purposes only and does not constitute medical advice. It is not intended to be a substitute for professional medical diagnosis or treatment. Always consult with a qualified physician regarding any health concerns or before starting any new treatment. Reliance on any information provided on this site is solely at your own risk.